Searchable abstracts of presentations at key conferences in endocrinology

ea0025s9.2 | Doping: performance enhancing substances in sport and their detection | SFEBES2011

Compounds enhancing oxygen delivery

Hemmersbach Peter

For more than 25 years substances and methods enhancing oxygen delivery in the body have been of great concern in the fight against doping. The clear influence of an increased amount of red blood cells on physical performance, most obvious for endurance sports, has alerted the anti-doping authorities to put a high priority on efforts to disclose the administration of such doping practices.The annually updated WADA-prohibited list mentions several erythro...

ea0020p518 | Paediatric Endocrinology | ECE2009

A common deletion in the uridine diphosphate glucuronyltransferase (UGT) 2B17 gene is a strong determinant of androgen excretion in healthy pubertal boys

Juul Anders , Sorensen Kaspar , Aksglaede Lise , Garn Inger , Rajpert-deMetys Ewa , Hullstein Ingunn , Hemmersbach Peter , Ottesen Anne-Marie

Testosterone (T) is excreted in urine as water soluble glucuronidated and sulphatated conjugates. The ability to glucuronidate T and other steroids depends on a number of different glucuronidases (UGT) of which UGT2B17 is essential. The aim of the study was to evaluate the influence of UGT2B17 genotypes on urinary excretion of androgen metabolites in pubertal boys.Study design: A clinical study of 116 healthy boys aged 8 to 19 years. UGT2B17</i...